Endocrine Abstracts

Introduction: It’s known that type 2 diabetes is an independent risk factor for cardiovascular disease. Osteoprotegerin (OPG), a glycoprotein secreted mainly by osteoblasts, is also produced by heart muscle and vessels. Its role in the pathogenesis of atherosclerosis and future cardiovascular events is still discussed.Material and methods: The study was conducted in 113 patients (48 F, 65 M) with type 2 diabetes mellitus (DM2) and coronary heart dis...

Introduction: Diamond-Blackfan anemia (DBA) is a rare, inherited normocytic or macrocytic anemia due to aplasia of red cell lineage in the bone marrow. Patients with DBA are diagnosed with a hypocellular bone marrow with a significant absence of erythroid precursors typically in early childhood and require chronic treatment with corticosteroids and frequent blood transfusions. Chronic blood transfusions lead to iron-overload injury and DBA patients, therefore, require lifelong...